Using your system have you been able to express a variety of antibody types, including ones with kappa or lambda light chains?

Answer

Yes. Both MaxCyte scientists and our clients have expressed a range of antibodies, antibody-like molecules and Fc fusion proteins from a variety of species including human, rabbit and mouse.   In comparison studies with other transfection methods, flow electroporation generally leads to higher titers independent of the type of antibody molecule that is being expressed. GFP control transfections indicate that our technology results in higher efficiencies and cell viability, which very likely is a key contributing factor to the increased titers.

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