What do you think is the importance of having serum free and/or animal free media in clinical stem cell manufacturing?

Answer

Animal-free, chemically defined media would be the ideal choice for all stem cell manufacturing from the standpoint of consistency and control of materials. However, not all cells can be expanded and/or differentiated without serum or other animal derived materials. The use of animal derived materials is acceptable with the appropriate sourcing of materials and testing but most groups developing cell based therapies are working to minimize or remove serum and other animal proteins from their manufacturing process where possible.

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