Why do laboratories need to consider automating their CLD workflows?

Automation addresses key challenges in manual cell line development (CLD) workflows such as ensuring clonality and maintaining data traceability and integrity. These issues can be particularly difficult in manual workflows where errors can occur, but automation helps streamline these processes, enhancing reproducibility and reliability.

What are the benefits of automating a manual cell line workflow?

• Increased throughput: Automation allows for more samples to be processed simultaneously, boosting productivity.
• Reduced labor requirements: Fewer personnel are needed to oversee the automated workflow.
• Non-stop operation: Automated systems can run continuously outside of normal working hours.
• Scalability: With automation, laboratories can handle a higher capacity of projects.
• Reproducibility: Automated workflows reduce variability, ensuring consistent and reliable results.

What are the major challenges in automation?

• Maintaining quality throughout the workflow: Automated workflows can be long and complex, making it crucial to maintain consistent quality.
• Transitioning from manual to automated processes: Moving from manual to automated workflows often involves handling multiple devices and requires expertise in automation and programming.
• High initial costs: Automation systems can involve significant upfront investments and require proper service and support for successful implementation.

Do scientists need to upgrade their automation expertise to work with the C.STATION?

No, CYTENA’s C.STATION simplifies automation. It addresses the key challenges in integrating automation into manual workflows, requiring no in-depth automation expertise in software such as programming and managing complex software interfaces. The system is ready be operated immediately after installation and training, allowing any lab to integrate it readily with minimal additional support.

Isn’t automation only capable of handling individual tasks in CLD?

CYTENA’s C.STATION automates not just individual tasks like cloning, but the entire CLD workflow up to the selection of top clones.

Are automation projects complex to realize?

Not with CYTENA’s C.STATION. The platform fully automates CLD workflows, offering pre-configured workflows managed by easy-to-operate software. By combining liquid handling, incubators, and software, the station integrates seamlessly into your lab, making automation straightforward and manageable.

Do automation projects entail elevated initial costs?

While automation can require an upfront investment, CYTENA’s UP.SIGHT is a fully prepared device that can be integrated affordably into the C.STATION. This setup makes the transition to automation cost-effective and smooth.

Is Cytena’s automation solution only for large pharmaceutical companies?

No. CYTENA’s solutions are suitable for labs of all sizes, whether they seek to minimize manual labor, increase productivity, operate in a regulated environment, or stay at the forefront of technology. CYTENA’s flexible platforms can benefit labs with diverse needs.

Does CYTENA support the configuration of my workflows?

Yes. CYTENA offers preconfigured workflows featuring best-in-class instruments for mAb (monoclonal antibody) production, viral vector production, and cell therapy manufacturing. This ensures easy setup and operation while supporting GMP and CFR-11 compliance features.

What data management features does the C.STATION offer?

The C.STATION is equipped with the latest C.STUDIO software and Green Button Go (GBG Automation) which support traceability and documentation essential for FDA/EMA submissions. The station also includes a unique data management solution that ensures compliance with industry regulations, enhancing overall workflow transparency.

How quickly can a lab start using CYTENA’s C.STATION?

The installation and workflow pre-configuration of the C.STATION are handled via CYTENA’s single point of contact, allowing labs to begin using it typically within six months of placing an order. This rapid installation timeline minimizes downtime and accelerates automation implementation.

CYTENA’s C.STATION provides a flexible and scalable solution for automating cell line development, tailored to meet the diverse needs of modern laboratories.

To learn more about automating Cell Line Development Workflows, please see C.STATION