Hubrecht Organoid Technology or HUB is a non-profit company that was founded around Organoid Technology. This technology is based on the discovery of the LGR5 positive adult epithelial stem cell, first identified in the intestine by the group headed by Prof. Hans Clevers. After this discovery, Prof. Clevers’ lab developed a method to genetically stably expand the stem cells into organoid structures that functionally mimic the patient’s original healthy or diseased epithelium. HUB collaborates with a variety of partners, such as pharma industry, to improve pre-clinical drug development and to provide more effective clinical treatment of patients using organoids as a predictive diagnostic tool.