Are you running your process over the weekend/holidays? How long have you run the process continuously?
This question is part of the following Ask The Expert session:
Adapting manual cell line development workflows to automation
Answered by:
Company: Alexion Pharmaceuticals, Inc.
Job Title: Development Associate IV, Biological Process Development
Answer
We have not had the need to perform any plate manipulations/liquid handling outside of working hours. We have run plate manipulations/liquid handling through much of a working day. Cultures are processed by the automation system from plating through scale up, a process that takes up to 8 weeks.