Have you discovered any significant differences in cell health and growth between use of recombinant and native supplements?
This question is part of the following Ask The Expert session:
Incorporating recombinant proteins to produce blood-free media formulations for therapeutic cell types
Job Title: Cell Culture Scientist
Overall, we have not seen significant differences in cell health and growth between recombinant and native supplements. However, there are particular instances where we have seen better growth kinetics in the blood-free media versus xeno-free SFM and serum-containing media. This is due to the presence of undefined components in native supplements that are actually having adverse effects on cell growth.