Why there is no penetration of microbes below 10 micron defect size in the aerosol challenge test while the size of bacteria is smaller than 10 micron?
This question is part of the following Ask The Expert session:
How to Ensure Integrity and Sterility of Single-Use Assemblies for Manufacturings
Company: PALL Corporation
Job Title: Global Product Manager
Electric continuity data and previous scientific literature imply that surface tension prevents the formation of a liquid channel for a small defect which is likely the reason for non-penetration of aerosol-based microbes through a defect smaller than 10 micron inside sterile space.