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- Cool Tool – Lynx CDR Connectors to Improve Sterile Fluid Transfer in BiomanufacturingPosted 2 days ago
- Improving Glycosylation Patterns and Consistency Through Media OptimizationPosted 3 days ago
- Cool Tool – Online Cell Culture Media Formulation ToolPosted 1 week ago
- Video – Impact of Chemically Defined Media on Product QualityPosted 1 week ago
- Ask the Expert – Media Optimization Can Improve Glycosylation Patterns and Consistency to Impact Protein EfficacyPosted 2 weeks ago
- Digital Biomanufacturing Will Enable Tissue BioprintingPosted 3 weeks ago
- Video – When and Where to Optimize Cell Culture MediaPosted 3 weeks ago
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The Dish’s Weekly Biotechnology News Wrap Up – January 15, 2016
This week’s biotechnology news headlines include, pharmaceutical companies joining together to fight cancer, groups want biosimilar hearings in the House, developing an early stage cancer detection test, how biotechnology can help solve world hunger, Moderna wins $20M grant for RNA-based therapeutics, Enbrel biosimilar succeeds in late stage study, and Sanofi and Innate Pharma partner to develop cancer treatments.
Cell Culture Events
Wednesday, January 27, 2016
USA 12:00 Noon EST / 9:00 AM PST
Europe 11:00 AM CET / 10:00 AM London (GMT)
Asia 2:00 PM Seoul/ 1:00 PM Singapore (SGT)/ 10:30 AM India
Australia 4:00 PM Sydney (AEDT)
About this webinar:
Human mesenchymal stem cells (hMSCs) are currently the subject of many clinical trials world-wide, as researchers develop new treatments for a variety of regenerative and inflammatory diseases. The use of a completely defined, serum-free, xeno-free culture system for hMSCs is necessary to provide control over research variables and reduce the inconsistency inherent in serum-containing culture systems.
David Fiorentini will provide an overview of the novel NutriStem® MSC xeno-free, serum-free culture system, which efficiently supports initial isolation and optimal expansion of hMSCs from a variety of sources, while maintaining appropriate hMSC features, such as proper fibroblast-like cell morphology, phenotypic surface marker expression profiles, differentiation capacity, self-renewal potential, and genetic stability over time. In addition, he will also describe the MSCgo™ family of xeno-free, serum-free differentiation media for use in generating mature adipocytes, osteoblasts, and chondrocytes using hMSCs isolated from a variety of sources.
Who Should Attend?
- Any researcher culturing hMSCs isolated from bone marrow, adipose tissue, cord blood, Wharton’s Jelly, placental tissue, or other source
- Researchers interested in improving cell culture results and minimizing lot-to-lot variation between experiments
- Researchers interested in learning new techniques for isolation, culture, cryopreservation, and/or differentiation of hMSCs
- Researchers interested in working with xeno-free and/or clinical grade hMSC culture conditions
Register here – http://www.bioind.com/msc-webinar
PepTalk – January 18-22, 2016 – San Diego, CA
PepTalk: The Protein Science Week is one of the largest gatherings of protein science researchers in the world. It offers an array of education, innovation and networking programs, and provides many opportunities to scientists.
Tuesday, January 19th at 9:35
Hollow Fiber Perfusion Bioreactors; The Original Upstream Single Use Continuous Manufacturing Technology
Scott Waniger, Vice President, Bioservices, Cell Culture Company
Hollow fiber perfusion bioreactor technology has been used in the bioprocessing industry for 30+ years and continues to be used to manufacture regulated biologics worldwide. While the technology has many similarities to stirred tank bioreactors, it also offers significant advantages over traditional technologies for many applications. The presentation will describe these advantages while explaining the setup, daily operation, and turn-around of this accepted technology within the bioprocessing industry. A case study showing steady state production of a monoclonal antibody (IgG) using hollow fiber bioreactors will be included.
Cell Therapy Manufacturing – February 3-4, 2016– Brussels, Belgium
Cell Culture World Congress – February 23-24, 2016 –Munich Germany
The Cell Culture World Congress is where pharma, biotechs, researchers & innovative start-ups gather to develop new strategies and partnerships to advance biotherapeutic production, manufacture, and commercialisation. Join the largest cell culture event focused on producing new therapeutics and immunotherapies at a commercial scale and see where biologic manufacture is headed next.
Key speakers include:
Dr Stefan Wildt, VP, Global Head Technical Research and Development, Cell- and Gene Therapies, Novartis.
Bo Kara, Head Process Development, Advanced Therapy Delivery, GSK
Sam Wadsworth, CSO, Dimension Therapeutics
Dr Lorenz Mayr Vice President of Reagents & Assay Development at AstraZeneca
For more information download the brochure: http://bit.ly/1JJWO5y
Downstream Processing World Congress – February 23-24, 2016 – Munich Germany
The Downstream Processing World Congress 2016 will introduce new and exciting content focusing on innovation and development with an emphasis on new methods. Showcasing exciting new technologies such as purifying complex molecules, PAT, continuous purification, chromatography alternatives and new methods of purification. Content will include cutting edge research and even more case studies , over 40 presentations from those working in bioprocess in big pharma, interactive sessions with biotechs and will be collocated with the 6th annual Cell Culture World Congress.
Key speakers include:
Dr Mark Federspiel, Director, Viral Vector Production Laboratory, Department of Molecular Medicine, Mayo Clinic
Dr Yogesh Waghmare, Staff Scientist, Late Stage Process Development, Genzyme Sanofi
Nicholas Clarkson, Group Lead, Analytical Development, Oxford Biomedica
Prof Manuel Carrondo, Director, IBET
For more information download the brochure: http://bit.ly/1l5kQMx
ISBioTech 6th Spring Meeting – March 7-9, 2016 -Washington, DC
Three concurrent programs on:
– Cellular Therapies
– Viral Vectors & Vaccines
– Baculovirus Expression Technology
BPI West – March 14-March 17, 2015 – Oakland Marriott City Center, Oakland, CA
World Vaccine Congress – March 29-30, 2016 –Grand Hyatt– Washington D.C.
Check out the Top Blogs and Top Ask the Expert Sessions of 2015 –
“Some leading pharmaceutical companies are joining forces in an effort to speed the testing of new types of cancer drugs that harness the body’s immune system to battle tumors.”
If you like this story, please see our blog titled “Biomanufacturing CHO Media – A look at different approaches and optimization opportunities”
“Twenty-three patient groups Jan. 6 sent a letter to the House Energy and Commerce Committee asking for hearings on biosimilar drugs and patient safety as the FDA creates regulations to implement the biosimilars approval pathway.”
If you like this story, please see our blog titled “Cool Tool – Gibco Essential 8 Flex Stem Cell Media Eliminates Need for Daily Feeding”
“Some people see it as the holy grail in oncology — a simple blood test that can detect any kind of cancer at an early stage, when it is easiest to treat and possibly cure.”
If you like this story, please see our blog titled “Biomanufacturing Innovations are Plentiful at This Year’s BPI Conference”
“I am not your typical pro-GMO advocate. As a twice-over returned Peace Corps Volunteer who shops at farmers’ markets, is a certified yoga teacher, and has built a career around alleviating hunger and poverty in the developing world, you might immediately peg me as someone who believes the only way is the organic way.”
If you like this story, please see our blog titled “Cool Tool- Hybridoma cell growth and performance in reduced serum + Zap-SR”
“Moderna Therapeutics said today it received an initial $20 million grant from the Bill & Melinda Gates Foundation to develop a new affordable combination of messenger RNA–based antibody therapeutics geared toward preventing HIV infection.”
If you like this story, please see our blog titled “Exosomes: A Major Phenomenon Flying Under the Radar”
“Baxalta Inc and Coherus Biosciences Inc said their experimental biosimilar of Amgen Inc’s arthritis drug Enbrel met the main goal in a late-stage study.”
If you like this story, please see our blog titled “Hollow Fiber Provides a Sweet Spot for Several Biomanufacturing Applications”
“Sanofi has teamed up with Innate Pharma SA in an effort to develop cancer treatments using the body’s own immune system.”
If you like this story, please see our blog titled “You can teach an old dog new tricks: Vero cells for virus-based cancer vaccine therapies”