Can automation be used to increase throughput? I am just thinking for screening purposes, it could be limiting if it isn’t high throughput.
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Yes. Corning has used HTS Transwell-24 permeable supports for the generation of multiple ALI cultures in an automation-friendly format for throughput cell-based assay of both healthy and diseased airway epithelium. Literature is available on miniaturized 96‑Transwell air–liquid interface human small airway epithelial model using semi-automated cell seeding and automated long term maintenance of ALI cultures in 96‑Transwell plates.
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