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When it comes to scaling-up your big idea, you need a supplier who is as comfortable in the production suite as in the lab. Corning brings together the broadest selection of vessels, surfaces, and media to create an end-to-end solution for scale-up of anchorage-dependent and suspension cells. Find out how we can help you increase productivity, lower risk, and get your scale-up right from the start.
Associated Experts
Associated Content
The Dos and Don’ts of Cryopreservation
We recently concluded our Ask the Expert session on The Dos and Don’ts of Cryopreservation. Cryopreservation is an integral activity in most cell culture labs. Cryopreservation permits the storage and keeping of cells, tissues, and 3D systems like organoids, for ... Continued
Scalable High Yield System for Mass Culture of Attachment-Dependent Cells
As increasing numbers of cell and gene therapies progress from research to clinical trials and on to commercialization, the need for efficient manufacture of high numbers of cells is critical. Many of the cells used in these therapies are attachment-dependent, ... Continued
A Look Towards the Future of 3D Cell Culture – A panel discussion
This article is the fourth in a series that was published in the eBook “3D Model Systems: Spheroids, Organoids and Tissue Models”. You can download all the articles in the series, by downloading the eBook. introduction and Overview Debbie King Researchers have used 2D cell ... Continued
Bringing 3D models into a High Throughput Environment
Elizabeth Abraham, Ph.D. - Senior Product Manager, Corning Life Sciences Elizabeth has been employed at Corning Life Sciences (CLS) since 2008 and has held multiple senior roles in various functions including R&D, Project Management and Business Operations. At CLS, she led ... Continued
Organoid Models: Getting Started and Culture Tips
This article is the third in a series that was published in the eBook “3D Model Systems: Spheroids, Organoids and Tissue Models”. You can download all the articles in the series, by downloading the eBook. An organoid is defined as an in vitro ... Continued
How to minimize contamination risk and protect your cultures
Dr. Elisabetta Difilippo is Scientific Supporting Specialist supporting EMEA regions at Corning Life Sciences. She assists in inquiries regarding products and applications of Corning Life Sciences portfolio, and she conducts scientific trainings. Dr. Difilippo graduated in Pharmaceutical Chemistry and Technology, and ... Continued
Spheroid Models: Getting Started and Culture Tips
This article is the second in a series that was published in the eBook “3D Model Systems: Spheroids, Organoids and Tissue Models”. You can download all the articles in the series, by downloading the eBook. It has been well established that three-dimensional (3D) ... Continued
3D Model Systems: Spheroids, Organoid and Tissue Model Systems
This article is the first in a series that was published in the eBook “3D Model Systems: Spheroids, Organoids and Tissue Models”. You can download all the articles in the series, by downloading the eBook. Culturing cells outside of their natural environment in ... Continued
Using Organoids for Disease Modeling
The culture of organoids has permitted researchers access to a highly physiologically relevant system for studying human disease. Human organoids reflect key structural and functional properties of organs such as kidney, lung, gut, brain and retina making them incredibly valuable, ... Continued
Spheroid Culture Advancements – Microplates
Spheroid cultures are on the rise as the success of 3D spheroids has been demonstrated in many areas of research including anti-cancer, drug screening, and in vitro tumor studies. With increase in use, has come the need for better tools to enable ... Continued
Corning® Nu-Serum™ I/IV Growth Medium Supplements for Reduced-serum Conditions with Fibroblast/Kidney Epithelial Cells
Introduction With the movement towards reduced-serum and serum-free conditions for cell culture, defined formulations and low-protein alternatives are of increasing value. Fetal bovine serum (FBS) is traditionally used as a supplement in media for cell and tissue culture at final concentrations ... Continued
A High Throughput System for CAR-T Cell Screening in Tumor Spheroids
Introduction Chimeric antigen receptor (CAR)-T cells which are engineered to recognize tumor cell-specific surface antigens, have shown promise to affect complete remission in patients with B-cell malignancies. With the recent FDA approval of Novartis’ Kyrmriah™ and Gilead Science’s Yescarta™, CAR-T Cell ... Continued
Cancer Research
Answers by: Corning experts Paula Flaherty, Technology Manager, Jeffrey Partridge, Senior Development Scientist and Hilary Sherman and Audrey Bergeron, Applications Scientists Introduction Unlocking the complexities of cancer is an ongoing challenge. Luckily, a countless number of researchers are working every day - ... Continued
Enabling Stem Cell Therapy Biomanufacturing using Dissolvable Microcarriers
Introduction Cell culture on microcarriers is an increasingly important technique for the production of large cell quantities and the scale-up of Cell Therapy applications. Microcarriers—small, spherical beads used to grow adherent cells in a suspension culture—offer several advantages for large-scale cell ... Continued
Going tiny is the next BIG thing: Tools and Techniques for Organoid Cultures
Answers by: Feng Li, Senior Scientist Development, Hilary Sherman, Applications Scientist, Himabindu Nandivada, Senior Development Scientist and Nitin Kulkarni, Sr. Scientific Support Specialist. Introduction In the last decade, organoid cultures have quickly become a popular way to create “mini-organs” to support the ... Continued
Matrigel – Tips, Tricks and Troubleshooting
We recently finished our Ask the Expert discussion, “Everything you ever wanted to ask about Corning® Matrigel® Matrix”. During this Ask the Expert session, we had a wide range of questions and discussed everything from storage and handling recommendations to ... Continued
A Novel 3D Immune Oncology Model for High Throughput Testing of Tumoricidal Capability
Introduction Immunotherapy, particularly for cancer treatment, is a very active area of both academic and clinical research. There has been increased interest in utilizing a patient’s own T cells to attack their tumors. However, positive laboratory results do not always translate ... Continued
Everything you ever wanted to ask about Corning® Matrigel® Matrix
Katie Slater and Paula Flaherty, Corning Introduction For the past 30 years, Corning Matrigel matrix has been used by researchers across the globe in essential applications through to cutting-edge, life-changing research. The number of citations for Matrigel matrix recently climbed over 10,000 ... Continued
Using the Corning HYPERStack Cell Culture Vessel and the Enhanced Attachment Microcarriers for Scale-Up and Production in the Vaccine Industry
Katherine E. Strathearn, Ph.D., Mansi Soni, and Mark E. Rothenberg, Ph.D. Corning Incorporated Introduction Viral transductions are used at the preclinical and clinical stages in the vaccine industry leading to an increase in demand to produce more virus more efficiently. The Corning® ... Continued
Novel ECM Mimetic Surfaces for Cell Expansion and Differentiation
Corning Life Sciences ASCB December 17, 2012 Marshall Kosovsky, Ph.D., Technical Support Manager Continued