I have heard that there can be problems with leachables in single-use bags and recently read a paper in which Amgen identified bDtBPP as a culprit in lowering viable cell density. How has the issue of leachables been addressed and what are plans moving forward?
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Stir Up Your Culture – Learn How to Succeed with Xcellerex Bioreactor Applications in a Manufacturing Environment
Company: Cytiva (formerly GE)
Job Title: Senior Manager
To date, we have not seen an issue with cell growth in Xcellerex products. Nevertheless, we have initiated efforts to interface with raw-material suppliers to better understand actions that might need to be taken to manage the specific issue that you have mentioned. These efforts are part of a larger mission to manage the overall supply chain for our products to assure product quality and availability. This is valid for both single-use products and multi-use products.