I have read about biosafety concerns about using lentivirus. How do you address those and does that mean any specific changes for employees working in the lab?

Answer

When working with lentivirus, it is important to establish a proper biosafety lab to conduct your research. BL2 or enhanced BL2 safety labs are typically appropriate in the laboratory setting for conducting research involving lentiviral vectors. The establishment of these labs should be done according to institutional biosafety guidelines at your research laboratory. Employees should be trained in how to handle and appropriately discard waste products and byproducts generated when using lentiviral vectors.