Platinum Sponsor
Thermo Fisher Scientific, Inc.
Thermo Fisher Scientific, Inc. is a global biotechnology company dedicated to improving the human condition. Our systems, consumables and services enable researchers to accelerate scientific and medical advancements that make life even better. Thermo Fisher Scientific customers do their work across the biological spectrum, working to advance the fields of discovery and translational research, molecular medicine, stem cell-based therapies, food safety and animal health, and 21st century forensics. The company manufactures both molecular diagnostic and research use only products.
Thermo Fisher Scientific provides industry-leading pharma services for drug development, clinical trial logistics, and commercial manufacturing through our Patheon™ brand. We partner with customers in the pharmaceutical, biotech, and life sciences industries as their trusted CDMO to deliver medicine to patients faster. https://www.patheon.com/us/en/home.html
Associated Experts
Job Title: Senior Scientist
Job Title: Senior staff scientist in R&D
Job Title: Vice President & General Manager, Cell Biology
Job Title: R&D Manager, Cell & Gene Therapy Platforms
Job Title: Senior Product Manager
Job Title: Global Marketing Development Manager
Job Title: Sr. Global Market Development Manager
Job Title: Area Director, Cell Therapy Logistics
Job Title: Product Manager of Global Research
Job Title: Senior Global Product Manager for Media Development Services, Bioproduction
Job Title: Scientist III, Cell Biology R&D
Job Title: Global Product Manager, Gibco PD-Express Services
Job Title: R&D Associate Director
Job Title: Associate Director of Cell Biology
Job Title: Research and Development Scientist III
Job Title: Field Application Scientist
Job Title: Director, Custom Products
Job Title: Director of Research and Development
Job Title: R&D Lead
Job Title: Staff Scientist, Research and Development for Cell Culture and Cell Therapy
Job Title: Senior Market Development Manager
Job Title: Field Application Scientist
Job Title: Sr. Global Market Development Manager
Job Title: Principal Scientist
Job Title: R&D scientist
Job Title: R&D Scientist
Job Title: Upstream Process Development Scientist
Associated Content
Streamline Your Media Selection: Discover the Right Fit with the GibcoTM MediaSelect Tool
Selecting the right media formulation is an essential part of optimizing cell culture conditions for both research and production workflows. With numerous variables to consider—such as cell type, media composition, formulation format, and the presence ... Continued
Best Practices for Cell Line Authentication
For academic researchers, biopharmaceutical companies, and institutional core facilities working with cultured cells, cell line authentication (CLA) is a critical quality control (QC) step. Proper authentication ensures that the cell line's identity is verified and ... Continued
CTS Detachable Dynabeads CD4 and CD8 Enable Flexible High-purity Isolation and Recovery of Target T Cells
As the field of cell therapy has evolved, our understanding of the interplay between CD8+ cytotoxic T cells and CD4+ helper T cells has changed. Although many therapeutic strategies initially focused on CD8+ T cells, ... Continued
Peptones: a powerful tool for manufacturing complex protein therapies
Introduction Peptones have emerged as a valuable media additive for a range of biopharmaceutical applications. They are a heterogeneous mixture of polypeptides, oligopeptides, free amino acids, trace metals, and nutrients derived from various sources, including yeasts, ... Continued
New Cell Culture Select Tool Simplifies Cell Culture Selection for Researchers
In this podcast, we spoke with Isha Dey, Senior Scientist, Cell Biology R&D, at Thermo Fisher Scientific about the challenges researchers face in selecting appropriate cell culture conditions due to variability in cell lines, lack ... Continued
Discover Optimal Cell Culture Conditions Efficiently with the New Online Cell Culture Select Tool
The ability to culture cells in vitro has allowed researchers to unravel the complexities of human biology, understand disease mechanisms, and advance drug discovery, which has led to countless breakthroughs in biomedical research. With thousands ... Continued
The Ongoing Importance of Cell Line Authentication
Cell lines are indispensable tools in both academic and industrial laboratories worldwide, forming the foundation of many breakthrough discoveries. However, cell line misidentification represents a longstanding and pervasive problem in basic and translational research that ... Continued
Celebrating 10+ Years of Innovation: Thermo Fisher Scientific’s Gibco Expi Protein Expression Systems
We had the privilege of sitting down with Sapna Padmanabhan, Sr. Global Market Development Manager at Thermo Fisher Scientific to talk about the Gibco™ Expi Protein Expression Systems, which have revolutionized protein production for over ... Continued
Optimizing Plasmid Production for Next-generation Therapeutics
Next-generation therapeutics such as cell and gene therapies and mRNA vaccines hold significant promise for the treatment and prevention of a wide variety of diseases. Further developing these therapeutic technologies and working toward improved manufacturing ... Continued
Consistency is key: Optimizing cell culture media manufacturing
Cell culture media play a pivotal role in the biopharmaceutical sector—providing the optimal cellular environments required to produce life-saving biologics. However, reliably sourcing media that are both high-quality and consistent can often present a major ... Continued
Development of a CHO Medium and Feed System Using Advanced Analytical Tools and Workflow Considerations
In this mini-webinar and accompanying article, Yoana Hammer, Scientist, Thermo Fisher Scientific, discusses the process of developing a new chemically defined cell culture media to support expression of monoclonal antibodies and recombinant therapeutics in a ... Continued
Solving the Solubility Challenge of Wnt Proteins with Gibco’s Wnt Surrogate-Fc Fusion Recombinant Protein
Wnt signaling is one of the key cascades regulating development and stemness during embryogenesis and is known to play a role in oncogenesis. Since their discovery, three Wnt signaling pathways have been characterized and all ... Continued
Gibco Cell Culture Basics Virtual Lab – A Great Example of the Benefits of Digital Training
Digital training tools are being popularized in the life sciences because of their accessibility, flexibility, and ability to foster learning across different competency levels and potentially in different geographical locations. The Gibco Cell Culture Basics ... Continued
Sophisticated multi-omics and bioinformatics-based CHO medium and feed enable a streamlined, highly productive mAb workflow
The new Efficient-Pro medium and feed system provides a complete and optimized solution for CHO cell–based mAb production, backed by a secured and robust supply chain to accelerate manufacturing workflows....Continued
New TransfectionSelect™ Product Selection Tool Takes the Guesswork Out of Improving Transfection Efficiency
Cell transfection is a powerful investigative tool used by many scientists to study gene expression and function across a wide range of applications from cell biology, cancer research, bioproduction of proteins and viruses to developing ... Continued
A new era for E. coli: Revolutionizing microbial bioproduction with chemically defined fermentation media
Overall, the innovation of CD microbial media has created a new paradigm of microbial bioprocessing. One which has the potential to not only continue the role of E. coli in the manufacture of life-saving biotherapeutics, but also to enhance its performance and safety and help transform the lives of even more patients....Continued
Optimization of conditions to support efficient HEK293 cell growth and adenovirus production
Overall, the results demonstrate Dynamis Medium to be effective for suspension HEK293 cell growth and adenovirus production. Optimal conditions may differ depending on the cell line and virus used. As a starting point, we recommend the following process parameters for multiplicity of infection (MOI), cell density, and feed concentration to maximize peak viral vector titers....Continued
Expedite Media Optimization with Viral Vector HEK Media Panel
Among viral delivery systems, recombinant adeno-associated viruses (AAVs) have become the preferred vector for gene therapy because of their high transduction efficiency, safety profile, and long-term gene expression. The increasing number of gene therapy programs ... Continued
Utilizing Optimized Protein Expression Systems to Advance Development of Therapeutics Against Infectious Diseases
The research summarized in the white paper underscores the need for robust and flexible transient protein production systems to support the rapid pace of infectious disease research, where optimized workflows to generate high-quality viral proteins can fuel research to better our understanding of viral pathogenicity and spread in efforts to produce effective therapeutic strategies....Continued
Fit for purpose, closed automated cell processing system provides improved cell therapy workflows for research through manufacturing
Much like monoclonal antibody manufacturing in the early 1980’s, cell and gene therapy manufacturing is constantly evolving with improved fit-for-purpose technologies being developed to meet expanding industry need. Despite smaller volumes, cell and gene therapy manufacturing is more complex and labor intense than protein-based biologics. Cell and gene therapy processing requires multiple steps and procedures including cell separation, concentration, washing and others. For a successful cell therapy to be produced, it is important to be able to conduct these activities as simply, safely and efficiently as possible....Continued
Ask the Expert – Maximizing efficient media optimization with AAV media panels
As gene therapies advance in both clinical successes and regulatory approval, there is a need to focus on increasing manufacturing efficiency. A key area to focus on is increasing viral vector titers, which ultimately will ... Continued
Best Practices – Cell Culture Techniques
Culturing cells in the laboratory is not a trivial task and success is dependent on a number of factors ranging from having the proper equipment, sterile technique, culture media, and conditions, to utilizing the appropriate protocols for handling the cells during passaging and freezing/thawing....Continued
The Rotea Counterflow Centrifugation System Offers a Versatile, Closed System Solution for Cell Therapy Processing
The Rotea system provides a flexible, cost-effective solution for cell therapy processing. Its closed single-use kit permits smooth transition from research through commercial manufacturing. Excellent support is also included with a field application scientist available to guide users through the system and the software to create a protocol for their specific applications....Continued
Demystifying the FBS Selection Process – A guide for evaluating product quality, origination and cost consideration
In this podcast, we talked with Chris Scanlon, Global Marketing Development Manager at Thermo Fisher Scientific about how to effectively evaluate which FBS product is right for each application. This includes weighing product quality levels and country of origin. Chris also shares strategies for maximizing purchasing options and new FBS products on the horizon....Continued
Best Practices for Rapid High Titer Protein Expression
Rich Altman and Matt McKenna, Field Application Scientists supporting the Expi Protein Expression Systems at Thermo Fisher Scientific talk about maximizing protein expression and achieving high titer in Expi expression systems....Continued
Media Optimization Strategies for Modifying Monoclonal Antibody Quality Attributes
Ways in which media components can be leveraged to achieve desired monoclonal antibody quality attributes and strategies for creating media formulations that provide good productivity as well as the desired quality profile....Continued
Best Practices for Being Productive and Staying Connected While Out of the Lab
Working from home can be very challenging, particularly if your work normally takes place in a lab. We were fortunate to have six cell culture researchers, who are part of Gibco’s Cell Culture Heroes program, ... Continued
New BenchStable™ Media Provides Flexibility and Convenience While Helping the Planet
Researchers looking for reduced cold storage space requirements and easier access to media on their bench top, now have an answer. Recently launched Gibco™ BenchStable™ media are specifically engineered for room-temperature storage. This permits flexible ... Continued
Spheroid Cell Culture – Practical solutions for frequently asked questions
The past decade has seen an increase in publications recognizing the value of culturing cells in three dimensions (3D) and the use of these 3D cell culture models has shown utility in many areas of ... Continued
Basic Fibroblast Growth Factor—the Good, the Bad and the Stable
A guest article by the Research & Development team at Thermo Fisher Scientific What is Fibroblast Growth Factor? In order to answer this question, first let’s discuss the definition of fibroblast. Fibroblasts are the type of cell ... Continued
Using cell culture models of endocrine resistance to improve triple positive breast cancer treatment options.
Gibco Cell Culture Hero, Dr. Hillary Stires discusses her work researching better treatment options for triple positive breast cancer patients. She explains how the use of cell culture modeling helps drive her research. She also talks about her experience as a cell culture hero and her passion for the scicomm movement on social media platforms....Continued
A New Dimension of Cell Culture: The Rise of Spheroid Culture Systems
In this article, we discuss the evolution of spheroid culture systems, methodologies of spheroid formation, spheroid culture challenges and relevant solutions. Historically, much of the knowledge we have on cellular processes is from experiments where cells ... Continued
Eliminate Contamination and Improve Efficiency with Gibco™ One Shot FBS
The bottles are engineered to tolerate the freeze/thaw process, which mitigates the potential of bottles cracking or lids popping off, which can happen with conical tubes especially when they are overfilled....Continued
Intelligently Designed Cell Culture Dishes Address Common Cell Culture Scientists’ Complaints
The EasYDish, launched earlier this month, by Thermo Fisher Scientific has some unique, smart design features to improve handling, stacking and transporting of cell cultures in the lab....Continued
Online Cell Culture Media Formulation Tool
Finding the right combination of cell culture media ingredients can be tricky and it isn’t always simple to find an off the shelf medium that meets all your requirements. Sometimes it takes several clicks around ... Continued
Cell Culture Basics Virtual Lab
The Cell Culture Basics virtual training lab is an introduction to cell culture, covering many topics including Basic principles of cell culture, Preparing a new cell culture, Performing a cell passage, and Cryopreservation.
...Continued
Gibco Essential 8 Flex Stem Cell Media Eliminates Need for Daily Feeding
Launched earlier this year, Essential 8 Flex is a highly optimized, xeno-free and feeder-free pluripotent stem cell (PSC) medium that eliminates the need for weekend feeding. The formulation is based on the Essential 8 medium published ... Continued
Achieve gram per liter protein yields in a transient CHO system
Introduction CHO cells are the predominant host for biotherapeutic protein expression, with roughly 70% of licensed biologics manufactured in CHO. Multiple attributes make CHO cells desirable for bioproduction including the ability to adapt to high-density suspension ... Continued
Improve lentiviral production using Lipofectamine 3000 reagent
LentiVirus is extremely versatile and efficient transfection method to work in more biologically relevant cells. However, they can be difficult to produce. Invitrogen™ Lipofectamine™ 3000 Transfection Reagent can help improve lentivirus production. In addition to being ... Continued
Improving Live Cell Fluorescence Imaging
Introduction Live cell fluorescence imaging provides the opportunity to study cellular function, however there can be challenges with the ability to image weak fluorophors without damaging the health of your cells. During this Ask the Experts session, ... Continued
Directed Differentiation of Pluripotent Stem Cells
Introduction The promise of human pluripotent stem cells will be realized only when these cells are successfully coaxed into different cell types found in the human body, through the process of directed differentiation. This is critical ... Continued
Transient Protein Production in Mammalian Cells
Introduction This Ask the Expert will address questions in regards to transient protein production in mammalian cells. Mammalian transient expression allows for the rapid generation, purification, and characterization of milligram to gram quantities of secreted or ... Continued
Minimize the Impact of Stress on Pluripotent Stem Cell Health in a Range of Workflows
Thermo Fisher Scientific’s PSC Cryopreservation Kit (Cat #A26446-01) contains a ready-to-use, xeno-free PSC Cryomedium coupled with an animal-origin-free, chemically-defined recovery supplement−RevitaCell™ Supplement (Cat #A26445-01). When used together, these solutions provide optimum cryopreservation and recovery of PSCs, minimizing loss of cell viability and thus maximizing post-thaw recovery....Continued
PSC Stress Management: Minimizing the Impact of Stress on Pluripotent Stem Cell Health in a Range of Workflows
Introduction Have you ever wished you had a safety net for your pluripotent stem cells, suffering loss of a cell line during processes such as cryopreservation, electroporation, or single cell passaging? While stem cells have a ... Continued
Efficient cell specific differentiation systems for iPSC
Introduction The promise of human pluripotent stem cells will be realized only when these cells are successfully coaxed into different cell types found in the human body, through the process of directed differentiation. This is critical ... Continued
Options for Identification and Characterization of Pluripotent Stem Cells
Introduction The vast advances in technologies for the efficient generation of footprint-free induced pluripotent stem cells (iPSC) have led to the creation of several iPSC lines from varying sources, genetic backgrounds, and derivations in different medias ... Continued
10 Things You Should Know About Dry Shippers Before Shipping High Value Biologics
As the biotech world has grown, the need to ship high value cell- and tissue-based materials has increased exponentially. An invaluable tool in the quest to move material in a safe and effective manner is ... Continued
Pluripotent stem cell (PSC) culture
Introduction Pluripotent stem cell (PSC) culture has evolved over the past decade, just as stem cell researcher needs have been changing and the market has been growing. Initial culture conditions for stem cells used FBS and mouse ... Continued