We are using a scaffold-free method for culturing our cardiac spheroids and are having problems getting uniform size, which is leading to inconsistent information and uneven distribution of nutrients. Do you have any suggestions?
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Bringing 3D models into a High Throughput Environment
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Scaffold-free products like Corning® spheroid microplates and Corning Elplasia® plates have specialized geometries that are designed to create uniform spheroids. The unique well geometry forces cells to evenly settle into the cavities to form consistent spheroids. Flat bottom scaffold-free products do not feature specialized well geometries, which typically results in many non-uniform 3D structures.
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