
Transferrin Improves the Performance of Serum-Free Media
Iron Compound | Growth Ratio |
---|---|
None | 100 |
Transferrin | 393 |
Ferric citrate | 311 |
Ammonium iron citrate | 249 |
Ferrous sulfate | 155 |
Iron (III) sulfate | 135 |
Ferrous ammonium sulfate | 99 |
Ammonium iron (III) sulfate | 102 |
Iron (III) chloride | 87 |
Iron (II) chloride | 105 |
Iron (III) diphosphate | 65 |
Footnotes
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1. Garcia-Alfonso, C., J. Lopez-Barea, P. Sanz, G. Repetto, et al., Changes in antioxidative activities induced by Fe (II) and Fe (III) in cultured Vero cells. 1996. (8661525) Arch Environ Contam Toxicol. 30 (4): p. 431-6.
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2. Conrad, M.E., J.N. Umbreit, and E.G. Moore, Iron absorption and transport. 1999. Am J Med Sci. 318 (4): p. 213-29.
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3. Elliott, R.L., M.C. Elliott, F. Wang, and J.F. Head, Breast carcinoma and the role of iron metabolism. A cytochemical, tissue culture, and ultrastructural study. 1993. Ann N Y Acad Sci. 698: p. 159-66.
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4. Eto, N., K. Yamada, T. Shito, S. Shirahata, et al., Development of a protein-free medium with ferric citrate substituting transferrin for the cultivation of mouse-mouse hybridomas. 1991. Agric Biol Chem. 55 (3): p. 863-5.
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5. Kovar, J. and F. Franek, Growth-stimulating effect of transferrin on a hybridoma cell line: relation to transferrin iron-transporting function. 1989. (2721585) Exp Cell Res. 182 (2): p. 358-69.