All About CHO – Everything from the basics to troubleshooting

Sponsored by: Life Technologies
Session ends: Closed
Answers by: Timothy Fawcett, Ph.D., Director, BioTechnical Institute of Marylandd (BTI)

Introduction

In the years since CHO based biopharmaceutical manufacturing began in the 1980’s, the technology has come a long way. Despite continual improvements over the years, including advances in equipment, cell line development practices, and media formulation, gains can still be made in CHO based manufacturing. CHO remains, by far, the most popular cell line for best selling biologics on the market today and as such it is imperative that we continue to find ways to improve on product yield, product quality, cost, and a myriad of other manufacturing challenges. If you are looking for ways to improve your CHO cell line or have a challenge to share, please join us for our Ask the Expert session on everything CHO.

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This session is sponsored by
Life Technologies


Questions & Answers

Hi, I am wondering if the CHO genomic sequence known?

This is a good question and the answer is yes! The paper by Xun Xu et al., Nature Biotechnology, Vol 29, No 8, 201, pg 735. reports that a CHO-K1 ancestral cel line was sequenced. There were 24,383 predicted genes. What is very interesting about the paper is that the authors focused on investigating genes […]» Read More