In an era where industries are increasingly driven by data and automation, the bioprocessing sector is embracing digital transformation to streamline workflows and improve productivity. However, blending the complex and highly regulated world of bioprocess with digitalization poses unique challenges. In this podcast, we talk to Dr. Simon Wieninger, Head of Portfolio and Applications at Eppendorf SE about how the journey toward digital integration requires well-defined goals, user-centered design, cross-industry learning, and, crucially, trust.

Setting Clear Goals: Purpose-Driven Digitalization

“Digitalization shouldn’t happen for digitalization’s sake,” Dr. Wieninger advises. While the temptation to adopt cutting-edge technology is high, each digital tool or system must serve a specific purpose. For bioprocessing organizations, establishing these objectives upfront is critical to ensure that digital investments yield meaningful results. Whether the aim is to boost productivity in production facilities, refine R&D processes, or improve operational efficiency in support functions like HR, having clearly defined goals anchors digital efforts in purpose.

This intentional approach is especially significant for production and R&D sectors within bioprocessing. Here, digitalization can streamline processes such as real-time data monitoring, automated adjustments to culture environments, and improved reporting and compliance tracking. By aligning digital goals with broader business objectives, organizations can make more effective use of resources and ensure that digitalization contributes positively to organizational growth.

Bridging Skill Gaps and Building Trust: Making Digital Tools Accessible

A successful digital transformation relies on the people who will use these tools day-to-day. However, not everyone in bioprocessing has a background in software or programming. Simon points out that for digital tools to be effective, they must be intuitive and accessible to all team members, from scientists in the lab to technicians on the production floor. “We need to design solutions that everyone can use,” he says, noting the importance of user-friendly interfaces that require minimal technical knowledge to operate.

Part of building an accessible digital framework is understanding the varying comfort levels with technology within the workforce. Some employees may be tech-savvy, while others are less familiar with digital tools. Recognizing and accommodating these differences is crucial to creating a smooth transition. Moreover, as Simon explains, trust is fundamental—not only trust in digital tools but also in the partnerships with vendors and technology providers who support this transformation. Organizations should leverage the expertise of these partners, building collaborative relationships to create solutions that meet specific needs and ultimately make bioprocess workflows more efficient.

Learning from Other Industries: Adopting Best Practices in Automation and Standards

The bioprocess industry has much to learn from sectors like automotive, finance, and telecommunications, which have long relied on automation and standardized processes to boost efficiency. In automotive manufacturing, for instance, high levels of automation allow for the production of thousands of vehicles with minimal human intervention. Bioprocessing, by contrast, has historically been more manual and labor-intensive, particularly in R&D and small-batch production.

According to Simon, one of the greatest opportunities for bioprocessing is to adopt industry standards that facilitate automation and improve interoperability across devices. One such example is the OPC (Open Platform Communications) standard, widely used in other sectors for seamless communication between devices. Applying such standards to bioprocessing could simplify data integration across lab instruments and production equipment, allowing researchers to capture and analyze critical information more efficiently. Additionally, industry leaders could set standards for digital protocols and automation practices, which would pave the way for faster digital adoption across the field.

Addressing Regulatory Challenges: Transforming Compliance through Digitalization

The bioprocess industry operates under stringent regulatory standards, which some view as an impediment to digital innovation. However, Simon argues that regulatory requirements shouldn’t be seen as obstacles but rather as factors that digital solutions can help address. In industries like finance and insurance, also highly regulated, companies have successfully incorporated digital tools to streamline compliance. Similarly, in bioprocessing, digital platforms could help standardize and organize the data needed for regulatory filings, potentially reducing the time and resources required for compliance.

Digital solutions, including cloud-based platforms and automated data management systems, could be particularly transformative in regulatory processes. By harmonizing data and ensuring accuracy across workflows, digital tools can make compliance not only faster but more consistent. Additionally, some regulatory bodies are already engaging in discussions about how to incorporate technologies like AI and machine learning into compliance filings. Although these innovations may require time to be fully accepted, regulatory agencies are increasingly open to exploring how new technologies can support safe and efficient bioprocessing.

The Power of Digital Twins: Small Steps Toward Big Goals

A popular concept in many industries, “digital twins” offer exciting potential for bioprocessing. These digital replicas of physical systems enable real-time monitoring, predictive maintenance, and even scenario modeling. Yet, as Simon notes, digital twin technology is still relatively new to bioprocessing, and its implementation will require gradual steps.

In the construction industry, for example, a similar concept known as BIM (Building Information Modeling) integrates all data related to a building project, from design specifications to material inventories, making it available to all stakeholders. While bioprocessing might not yet be ready for an all-encompassing digital twin platform, companies can start small—implementing digital twins for specific workflows or equipment and gradually expanding over time. This incremental approach can yield immediate benefits while setting the foundation for larger-scale digital initiatives.

Embracing Cloud Technology and Real-Time Monitoring: Moving to Industry 4.0

Cloud platforms and AI have been at the forefront of Industry 4.0 for years, but only recently has the bioprocessing industry begun to fully embrace these technologies. Cloud storage allows for centralized data management, enabling teams to access information from any device, anywhere. This flexibility has profound implications for researchers and technicians, who can now monitor processes remotely. “Imagine checking on a bioreactor’s status from your phone while you’re out with your family,” Simon explains. This real-time access not only enhances convenience but also provides peace of mind to scientists who can verify that their cultures are growing as expected.

AI-powered real-time monitoring and data analysis tools also have significant benefits for process efficiency and productivity. By automating data capture and analysis, these technologies enable faster decision-making and reduce the likelihood of errors. Over time, the integration of cloud-based tools and automation could lead to smarter, more efficient bioprocessing workflows. With every iteration, companies will gain a better understanding of how to refine and optimize these processes, driving the industry toward more consistent and scalable digital practices.

The Future of Bioprocessing: A Hybrid of Digital and Analog

Looking ahead, Simon envisions a future where bioprocessing laboratories achieve a balance between digital and analog technologies. While complete digitalization may not be feasible—or even desirable—within the next five years, incremental advances in data processing and automation will help researchers and technicians become more efficient and productive. Automation, particularly in areas like sampling, data integration, and real-time monitoring, will streamline lab work, allowing scientists to focus on research rather than routine tasks.

Ultimately, the goal of digital transformation in bioprocessing is to bring life-saving therapies, such as cell and gene therapies, to market faster. By reducing time spent on data management and process optimization, digital solutions empower scientists to concentrate on breakthrough discoveries. As data standards and digital infrastructure improve, the industry may also see an increase in collaborative projects, as cloud platforms make it easier for teams from different locations, and even different companies, to share data securely.

A Call to Collaboration: Sharing Knowledge for a Digital Future

Closing with a call to action, Simon invites bioprocess professionals to reach out, share insights, and learn from each other’s experiences with digitalization. “Digital transformation has incredible potential to accelerate progress in the bioprocess industry, and I’m excited to be part of that journey,”. By fostering a collaborative spirit and supporting each other in the quest for effective digital solutions, bioprocess organizations can collectively improve human health outcomes and bring new treatments to the world more rapidly.

In the end, bioprocessing’s journey toward digital transformation is not just about adopting new tools—it’s about building an industry that is faster, more resilient, and better equipped to meet the challenges of tomorrow.