We make point-of-need-devices ranging from rugged, handheld chemical detection tools to compact, tiny footprint analyzers and fast separation devices. These uncomplicated purpose-built devices provide users with the power to redefine their workflows by getting actionable answers at the point of need. Our devices are being used for critical applications across the globe in the life sciences and field forensic markets. 908 Devices is headquartered in the heart of Boston, where we research, design and manufacture innovative products based on high-pressure mass spectrometryTM (HPMS) and microfluidic separation technology. For more information, visit 908devices.com.
During the recent ASGCT virtual conference, there was an informative symposium focused on mass spectrometry (MS)-based strategies for in-process analytics to support cell therapy manufacturing development and optimization. Rich Rogers, Ph.D., from Bristol Myers Squibb (BMS) gave an excellent presentation outlining the analytical needs and instrument requirements for PAT and how MS-based PAT holds promise as a robust technique to overcome many of the challenges experienced with current analytical tools.
Rich and Kerin showcased the need for instrumentation to further process development and PAT in-process monitoring. They demonstrated how the REBEL analyzer is being used to provide rapid, sensitive at-line measurements for spent media metabolite analysis, and for nutrient profiling during media optimization or reformulation for viral vector and CAR-T manufacturing....Continued
In this podcast, we talked with Dr. Glenn Harris, Director of Integrated Life Sciences Platforms at 908 Devices, about the benefits and challenges of implementing rapid media analysis in process development, including the bottleneck created by outsourcing samples to core labs. We also discussed an easy to implement, benchtop media analyzer that permits comprehensive media analysis in real-time, thus speeding process development efforts....Continued
To speed process development using real-time analytics, 908 Devices launched its Rebel analyzer. The Rebel™ provides comprehensive at-line fresh and spent cell culture media analysis for bioprocess labs. This offers a high-throughput solution for media analysis....Continued