Gold Sponsor
908 Devices
We make point-of-need-devices ranging from rugged, handheld chemical detection tools to compact, tiny footprint analyzers and fast separation devices. These uncomplicated purpose-built devices provide users with the power to redefine their workflows by getting actionable answers at the point of need. Our devices are being used for critical applications across the globe in the life sciences and field forensic markets. 908 Devices is headquartered in the heart of Boston, where we research, design and manufacture innovative products based on high-pressure mass spectrometryTM (HPMS) and microfluidic separation technology. For more information, visit 908devices.com.
Associated Experts
Job Title: Director of Integrated Life Sciences Platforms
Associated Content
Predictive forecast model strategy to enhance process control and refine feeding strategy of essential amino acid in CHO cell cultures
Chinese Hamster Ovary (CHO) cells are an invaluable cell line for robust and reliable production of therapeutic proteins in the biopharmaceutical industry. There is significant pressure on the industry to accelerate process development to increase ... Continued
Cell Culture Media Analysis for Gene Therapy
In-depth characterization could aid in optimization efforts to decrease COGS and improve the productivity of host cell lines through better understanding of nutrient requirements or to facilitate process development efforts such as adapting adherent cells to suspension culture and more. Ideally, the media selected should provide the essential nutrients to facilitate high productivity, consistency and quality as well as being amenable to support scale up to larger manufacturing platforms....Continued
Cell Culture Media Analysis for Cell Therapy Applications
This article was originally published in the eBook “What's In Your Media”. You can download all the articles in the series, by downloading the eBook. In the field of regenerative medicine, cell therapies are increasingly becoming viable therapeutic ... Continued
Cell Culture Medium Development and Analysis for Bioproduction
Much of the increase in productivity since the start of the bioproduction era decades ago has been due to optimization of cell culture media to support cellular health and to maximize product productivity and quality. With this advancement in media formulation and feed strategies, there is increased need for robust analytical tools. Many of the classical methods of media analysis were burdensome, slow, expensive, and limiting....Continued
The Critical Role of Cell Culture Media Development and Optimization
Cell culture media remains a key component of biologics-based therapeutics manufacturing. As such, cell culture media development and optimization continue to be important focuses for the biopharmaceutical industry. Increased analytics capabilities have provided new insights into the relationship between cell culture media, the cells they support, and ultimately, the outcome of the final biologics product. That greater insight offers more opportunities to create products faster, more cost effectively, and with greater therapeutic success....Continued
Cell Culture Media Analysis in Upstream Biologics Development
This article summarizes key takeaways from the discussion and highlights areas that the panelists identified as challenges and opportunities for improvement....Continued
In-Process Analytics are Key to Successful Cell Therapy Process Optimization and Manufacturing
During the recent ASGCT virtual conference, there was an informative symposium focused on mass spectrometry (MS)-based strategies for in-process analytics to support cell therapy manufacturing development and optimization. Rich Rogers, Ph.D., from Bristol Myers Squibb (BMS) gave an excellent presentation outlining the analytical needs and instrument requirements for PAT and how MS-based PAT holds promise as a robust technique to overcome many of the challenges experienced with current analytical tools.
Rich and Kerin showcased the need for instrumentation to further process development and PAT in-process monitoring. They demonstrated how the REBEL analyzer is being used to provide rapid, sensitive at-line measurements for spent media metabolite analysis, and for nutrient profiling during media optimization or reformulation for viral vector and CAR-T manufacturing....Continued
Rapid At-line Media Analyzer Speeds Process Development by Eliminating Analytics Bottleneck
In this podcast, we talked with Dr. Glenn Harris, Director of Integrated Life Sciences Platforms at 908 Devices, about the benefits and challenges of implementing rapid media analysis in process development, including the bottleneck created by outsourcing samples to core labs. We also discussed an easy to implement, benchtop media analyzer that permits comprehensive media analysis in real-time, thus speeding process development efforts....Continued
The Rebel Analyzer Enables Real-Time Comprehensive Media Analysis in a Benchtop Package
To speed process development using real-time analytics, 908 Devices launched its Rebel analyzer. The Rebel™ provides comprehensive at-line fresh and spent cell culture media analysis for bioprocess labs. This offers a high-throughput solution for media analysis....Continued