Are there any animal-free/synthetic surfaces that are suited for growing organoids?
This question is part of the following Ask The Expert session:
Going tiny is the next BIG thing: Tools and Techniques for Organoid Cultures
Corning® Matrigel matrix is one of the most successful animal based extracellular matrix that has been used to culture organoids. There are multiple reports on engineering a synthetic matrix to grow organoids with the studies being compared to their morphology/functionality in Matrigel matrix. Researchers have succeeded in generating them for a specific organoid or application and there is a lot of ongoing work. Example can be found in references listed below.