Are TAL-meditated KO or KI strains considered to be GMO?
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Choosing the Right Genome Editing Technology for your Application and Research
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KO and KI involves editing the native genetic code by either mutating or deleting a encoded message or inserting a new piece of information at a desired site. Although this does manipulate the native genetic information, this technology when used in a responsible manner has very useful applications like engineering yeasts for insulin production or engineering cells for more economiocally and clinically valuable products.