Do you think this technology has the potential to eliminate or reduce animal testing?
This question is part of the following Ask The Expert session:
Using Intestinal Organoids for Intestinal and Stem Cell Research
Answered by:
Answer
Yes, this technology definitely has the potential to reduce animal testing. Many experiments from developmental biology to drug screening can be performed on organoids rather than primary mouse culture. Organoids offer a “clean” system that allows for testing of drug effects on the intestinal epithelium alone, without any potential side-effects seen when doing animal testing. It is premature to say elimination as some experiments inherently require animal models for complex investigations, but organoid technology is clearly moving drug testing in an ethical direction.