How do you calculate cell specific perfusion rate?
This question is part of the following Ask The Expert session:
Utilizing N-1 Perfusion to Increase Productivity and Intensify Processes
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Company: Catalent Biologics
Job Title: Director, Process Development Department
Answer
Perfusion rate depends on cell line and culture media. It should be estimated for optimal growth rate and productivity. A good source that advises steps to determine perfusion rate are here: https://www.repligen.com/technologies/xcell-atf/FAQ-perfusion