I am using chemically defined media for our CHO-S pilot scale manufacturing. I am not happy with the titers, but don’t have the time to do more process development. Do you have any recommendations for quick things to try to raise productivity? Ideally it would be something I could just add to the media or feed.

Answer

There are a number of feeds on the market. Most major suppliers of cell culture media will have some type of feed to go with their protein expression media intended for scale productions.