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We currently work with an upper limit of 25L (replacing up to 6,000 roller bottles), and have found that this more than accommodates most customers’ applications in the human and animal vaccine business. In other words, it is not a limitation.
In reality, there is a geometric limitation on how large it could be. While it would be possible to scale this up to 50L in the future, it would not make sense to go any larger than that from an applications and engineering perspective.