What are the pros and cons of using internal vs external threaded cryovials?
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The Dos and Don’ts of Cryopreservation
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The two options are a matter of preference. Some researchers choose external thread designs since nothing gets inserted into the vial which may help minimize contamination. Some researchers choose internal thread designs because they fit better in their freezer boxes. If someone uses automation, they need to consider what thread can be used with their instrument grippers.