What kind of process optimization do you recommend for using perfusion in manufacturing? I have seen data that you can get good results with less development time. Do you agree?
This question is part of the following Ask The Expert session:
Utilizing N-1 Perfusion to Increase Productivity and Intensify Processes
Answered by:
Company: Catalent Biologics
Job Title: Director, Process Development Department
Answer
The development and optimization required to implement a perfusion system in manufacturing depends on different factors including the molecule and cell line. Depending on those factors, cell culture process prior knowledge and, if available, platform knowledge can be leveraged to reduce or improve efficiency of development and scale up of the perfusion process.
This post is sponsored by Catalent Biologics.