This past year we really got our podcast channel going with several great podcasts on upstream and downstream biomanufacturing, stem cell culture, Cell Therapy and drug discovery. We always include interesting show notes and the option of listening from your computer, so please check these out, even if you don’t want to download to a mobile device. I have listed our most popular podcasts here in alphabetical order.

Bioengineered organ implants poised to change treatment paradigms in esophageal cancer

In this podcast, we interviewed Jim McGorry, CEO and Saverio LaFrancesca, President and Chief Medical Officer about how Biostage is using Cell Therapy to improve the standard of care in adult and pediatric esophageal disease.

Do you have to sacrifice antibody titer for quality? Employing cell biology to get the best of both worlds

In this podcast and accompanying article, we interviewed Dr. Adam Elhofy, Ph.D., Chief Scientific Officer, Bio-Ess Laboratories, about the relationship between antibody titer and product quality attributes such as glycosylation. Dr. Elhofy shares his thoughts on both challenges and opportunities in optimizing for both high titer and glycosylation profiles.

Enabling Viral Vector Production and Vaccine Manufacturing using the iCELLis – a single-use, automated, and closed manufacturing platform

In this podcast, we were fortunate to have a group of experts for a panel discussion on vaccine manufacturing and viral vector production.

FBS – It’s not all created equal – what consumers need to know

In this podcast and accompanying article, we interviewed Alyssa Master, Ph.D., Senior Manager of Science and Applications, Nucleus Biologics about some of the challenges of working with FBS, why not all FBS is created equal and suggestions for FBS customers who are trying to navigate these issues.

Implementation of single-use bioreactors for microbial fermentation is easier than you think

In this podcast and accompanying article, we interviewed Ken Clapp, a senior member of GE Healthcare Life Sciences’ upstream product management team. We explored in more detail the implementation of single-use systems for microbial fermentation including which processes make good candidates for single-use and considerations for transitioning from stainless steel.

Improving lab productivity and reproducibility by taking a fresh look at existing workflows and protocols

In this podcast, we interviewed Sarah Simons, Automation Field Project Manager, Beckman Coulter Life Science, about how to improve lab productivity and reproducibility by “spring cleaning” your methods and taking a fresh look at existing workflows and protocols.

Novel technology enables encapsulated cell therapeutics without triggering fibrosis

In this podcast, we interviewed Dr. Paul Wotton, CEO, about Sigilon Therapeutics’ discovery platform. The platform combines cell engineering and biocompatible Afibromer^™ technology to enable cell therapeutics that do not trigger fibrosis.

Protein A Chromatography – A look at where we have been and where we are going

In this podcast and accompanying article, we interviewed Jonathan Royce,  Business Leader, Chromatography Resins, GE Healthcare Life Sciences, about the evolution of Protein A including the latest developments in Protein A chromatography resins. We also discussed what the future holds for this purification mainstay and how it can continue to address the changing needs of biopharma.

Resolving large scale buffer management challenges

In this podcast and accompanying article, we interviewed Joakim Lundvist, Modality Manager, BioProcess™ Hardware, GE Healthcare about large-scale buffer management challenges. Buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing as large volumes of buffers and process liquids are often required. So how can this be done in a more efficient way? How can more capacity be added to buffer preparation without adding major capital investment? Are there ways to reduce the manufacturing footprint and time spent on buffers? We examined the biggest challenges in buffer management and explored how technologies like inline conditioning can provide possible solutions.

Single-use bioreactors for fermentation – It’s now a reality that deserves consideration

In this podcast and accompanying article, we interviewed Ken Clapp, a senior member of GE Healhcare Life Sciences’ upstream product management team. We discussed the use of single-use bioreactors for fermentation, how single-use technology has evolved to meet the more rigorous demands of fermentation, and the benefits of single-use for this application.

Smart Cell Culture Monitoring – Transforming the way we look at cells in culture

In this podcast, we interviewed Philip Mathuis, Co-founder and CEO, Ovizio, about cell culture monitoring, the latest technology for monitoring cells in culture without the need for sampling and where monitoring could move in the future.