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Differentiating Human ES and iPS Cells to Pancreatic Progenitor Cells
Differentiating human embryonic stem (ES) or induced pluripotent stem (iPS) cells to pancreatic progenitors and downstream differentiated cells is a challenging and labor-intensive process. With the availability of a new differentiation kit that provides a standardized and straight-forward protocol, generating functional PDX-1+/NKX6.1+ pancreatic progenitor cells with high efficiency has become much easier.
In last week’s post, Cool Tool – New Robust Kit for Efficient Generation of Functional Pancreatic Progenitor Cells, the challenges in the field of pancreatic cell research were discussed along with how the new STEMdiff™ Pancreatic Progenitor Kit can address them. This kit efficiently differentiates multiple human ES and iPS cell lines to pancreatic progenitors that are capable of maturing into endocrine and exocrine cells. The new tool allows researchers to study pancreatic development and disease without having to worry about optimizing the cell culture conditions.
This week, Dr. Michael Riedel will be answering your questions about pancreatic cell differentiation including how to use the STEMdiff™ Pancreatic Progenitor Kit to ensure high efficiency differentiation and generate pancreatic progenitors for pancreatic research. If you have any questions regarding differentiating to the endoderm lineage, Dr. Riedel is happy to discuss that as well as he also oversees the STEMdiff™ Definitive Endoderm Kit that can be used to generate multipotent definitive endoderm (DE) cells.
Ask your questions about endoderm and pancreatic cell differentiation!