How do you recommend determining the starting perfusion rate for an antibody production process?
This question is part of the following Ask The Expert session:
Utilizing N-1 Perfusion to Increase Productivity and Intensify Processes
Answered by:
Company: Catalent Biologics
Job Title: Director, Process Development Department
Answer
Perfusion rate depends on cell line and culture media. It should be estimated for optimal growth rate and productivity. A good source that advises steps to determine perfusion rate is here: https://www.repligen.com/technologies/xcell-atf/FAQ-perfusion
This post is sponsored by Catalent Biologics.