Are there any alternatives to morphological selection that is more specific to fully reprogrammed cells?

Answer

The use of antibodies against surface markers of self-renewal is a convenient method to distinguish reprogrammed colonies. Typically the robust expression of SSEA4, Tra-1-60, and Tra-1-81 on the cell membranes is a more specific method of characterizing your cells.

For a complete list of PSC markers, please visit lifetechnologies.com/stemcellantibodies