I am interested in learning more about laminins, I think you offer these, and which types of culture they can be beneficial in.


There are several different formats of laminin available. Here is an overview of what Corning offers, whether vialed (murine), coated, or recombinant (human).

  1. Vialed products (mouse)

Corning® Laminin (mouse) is used as a thin coating on tissue-culture surfaces or as a soluble additive to culture medium. Laminin is a major component of basement membranes. It has numerous biological activities including promotion of cell adhesion, migration, chemotaxis, growth, and differentiation, including neurite outgrowth.

Here are links with more information on the offerings from Corning:


Laminin/Entactin High Concentration


  1. BioCoat™ surfaces

Use Corning® Laminin surfaces as a thin coating on tissue culture surfaces or as a soluble additive to culture medium to promote cell adhesion, migration, chemotaxis, growth, and differentiation. Laminin/Entactin Complex High Concentration (HC) is a special formulation that Corning has developed to enhance three-dimensional (3D) cell culture applications. Culturing cells in or on gels such as Laminin/Entactin Complex enable the study of specific mechanisms that dictate cell differentiation and functionality.

Applications include:

  • Promotion of neurite outgrowth
  • Reduction of fibroblast migration in neuronal cell cultures
  • Neural crest cell attachment
  • Gene expression in rat cortical neurons
  • Maintenance of undifferentiated pluripotent stem cells

To learn more about these Corning surfaces, please use the links below:

Corning Laminin Coating Surfaces

Corning BioCoat Surfaces

Specifications and ordering information:

Corning BioCoat Surfaces

Corning Laminin Coating Surfaces

  1. rLaminin-521 (human)  

Corning rLaminin-521 (Human) is a heterotrimer composed of α5, β2, and γ1 chains expressed in a mammalian cell culture system. rLaminin-521 (Human) supports long-term self-renewal of human pluripotent stem cells (hPSC), including embryonic stem cells (hESC) and induced pluripotent stem cells (iPSC) in defined and xeno-free environments. rLaminin-521 provides additional benefits, including ROCK inhibitor independent single cell expansion of PSCs, which improves hPSC culture ease and efficiency.  Corning rlaminin-521 is available in vialed formats as well as pre-coated 6-well plates.

Related Application Notes:

Corning® PureCoat™ rLaminin-521 Cultureware: A Ready-to-use, Animal-free Vessel Platform for the Culture and Single Cell Passaging of Human Pluripotent Stem Cells

Corning® PureCoat™ rLaminin-521 (Human) for Expansion and Differentiation of Human Neural Stem Cells

To learn more about this Corning surface, please use the link below:

Corning rLaminin-521, Human

Specifications and ordering information:
Corning® rLaminin-521, Human

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