What are the benefits of N-1 perfusion? Why do some companies want use N-1 perfusion as part of their process?
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Utilizing N-1 Perfusion to Increase Productivity and Intensify Processes
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Company: Catalent Biologics
Job Title: Director, Process Development Department
Answer
As the bioreactor is inoculated with higher cell density the duration of the bioreactor can be reduced achieving the same titer as in fed batch, alternatively higher titer can be reached with a longer duration in the feed batch when inoculated at higher cell density from a perfusion N-1
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