Gold Sponsor
Advanced Instruments
Advanced Instruments is a global company offering a novel portfolio of analytical tools including, OsmoTECH®, a robust line of micro-osmometers to support bioprocessing and quality control (QC), and Solentim, a portfolio of best in class imaging and single-cell deposition technologies for cell line development workflows and assurance of clonality for regulatory bodies.
Associated Experts
Job Title: Chief Commercial Officer
Associated Content
Automating Osmolality Monitoring in Upstream and Downstream Bioprocessing
Osmolality, the concentration of a solute in a given solvent, is a frequently monitored critical quality attribute (CQA) in bioprocessing. The need to test osmolality is present throughout upstream and downstream bioprocessing. However, many current ... Continued
The Newest Technology in Single Cell Seeding with Intelligent Cell Detection – VIPS™ PRO by Advanced Instruments. Built to Revolutionize Cell Line Development
Mammalian cells have been used to produce therapeutic recombinant proteins for over thirty years and during that time there has been significant advances in the technologies and methods used to engineer the cell lines and ... Continued
The Importance of Monoclonality in Cell Line Development: The Solentim VIPS Advantage
Single-cell cloning (SCC) is a critical step in monoclonal cell line development (CLD), which is widely used across the biopharmaceutical industry for production of recombinant proteins antibodies, vaccines, and for the development of stem cell ... Continued
Single-Step Cloning Strategy Speeds Timeline for Novel Vaccine Candidates
With the emergence of Covid-19 this year and the threat of other novel viruses looming on the horizon, now more than ever we need fast, efficient methods for generating novel vaccine candidates. These new methods ... Continued
Cell Line Development – A look at the evolution, new advances and future developments of this critical process step
In this written interview, Dr Ian Taylor, Chief Business Officer, Solentim, discusses the evolution of cell line development, new advances in technologies and workflows, and future advances. Our discussion includes improved imaging techniques, manual limiting ... Continued
Using transposases to generate clones with high, predictable expression and stability
Standard cell line development workflows include transfection followed by the screening of hundreds to thousands of clones, in an effort to find high producing clonal colonies that are stable and demonstrate specific attributes based on ... Continued
Optimising outgrowth of clones following single cell cloning ensures more predictable and effective cell line development
Successful cell line development is critical to effective CHO cell based biomanufacturing. To accomplish this, companies must identify cell lines that have good manufacturing potential via clone selection. Clones that warrant further investigation are those ... Continued
New Technologies and Trends in Cell Line Development
Informa’s Cell Line Development and Engineering conference last month was full of pharmaceutical companies and solutions providers sharing best practices, innovative solutions and emerging trends in Cell Line Development. I was pleased to attend the conference ... Continued
A single Cell Dispensing Unit for Cell Line Development – taking the benefits of Limiting Dilution and combining with high seeding efficiencies
Introduction Identifying cell lines that have good manufacturing potential is critical to successful CHO cell based biomanufacturing. To accomplish this, transfected cells must be separated and cloned into monoclonal cultures. Thorough clone selection is crucial to ... Continued