Cancer Research

Sponsored by: Corning Life Sciences
Session ends: February 2nd, 2018, 3:00pm MST
Answers by: Corning experts Paula Flaherty, Technology Manager, Jeffrey Partridge, Senior Development Scientist and Hilary Sherman and Audrey Bergeron, Applications Scientists

Introduction

Unlocking the complexities of cancer is an ongoing challenge. Luckily, a countless number of researchers are working every day – determined to understand the causes and behaviors of cancer in search of new and better ways to more effectively treat the disease.

Corning Life Sciences supports this important research with reliable lab products that deliver consistent, repeatable results. Matrigel® matrix, Transwell® permeable supports and spheroid microplates are just a few Corning products being used to create more in vivo-like 3D environments used in cutting edge cancer research studies.

This session is sponsored by

Corning Life Sciences

This week Corning experts will be answering your questions on cancer research – our scientists are ready to support you in areas ranging from 3D cell culture to tumor formation and angiogenesis to invasion/migration assays

About Our Experts

Corning experts include Paula Flaherty, Technology Manager, Jeffrey Partridge, Senior Development Scientist, Hilary Sherman and Audrey Bergeron, both Applications Scientists. Paula has extensive experience in developing cell based assays. Jeff has over 20 years’ experience in cancer research, including using animal models as well as in vitro invasion and migration systems such as Corning® BioCoat™ Matrigel® Invasion Chambers and Corning FluoroBlok™ Cell Culture Inserts. Hilary has extensive experience with cancer cell migration, immune oncology assays and 3D cell culture. Audrey has experience with cultures and applications of primary and engineered immune cells as well as with high throughput 2D and 3D assays


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Questions & Answers

At ISSCR this year, I went to a talk on co-culturing tumor spheroids and immune cells to create cancer models. I have also seen fibroblasts used in the same way. Do you have any resources to learn more about creating this type of model. I have seen papers on various models, but I am looking for resources for how to create these in the lab.

One of the simplest methods to create co-culture spheroids containing multiple cell types is to seed the different cell types together into a low attachment round bottom plate such as the Corning® spheroid microplate. The cells can be seeded at the same time or added at different time points. Here is an application note as […]» Read More

I am interested in learning more about laminins, I think you offer these, and which types of culture they can be beneficial in.

There are several different formats of laminin available. Here is an overview of what Corning offers, whether vialed (murine), coated, or recombinant (human). Vialed products (mouse) Corning® Laminin (mouse) is used as a thin coating on tissue-culture surfaces or as a soluble additive to culture medium. Laminin is a major component of basement membranes. It […]» Read More

I don’t have a specific question but was wondering if you could tell us about which promising new cancer research tools you think will make the most impact.

There are many exciting things happening in the cancer research space, but two areas that we feel will have the largest impact on cancer research in the next few years are through improved modeling and superior imaging. An interesting trend we have noticed, is that the technologies are not necessarily all new, but have been […]» Read More

There is a lot of expectation about modeling cancer organoids but is there an application of Corning Fluoroblok inserts to track immune therapy with an organoid culturing into Corning Biocoat Matrigel Invasion Chambers? In other words, can I culture an organoid in the inner compartment and then tracking the effect of the immune therapy?

Assuming you are looking to culture a cancer organoid in the apical chamber of Corning® FluoroBlok™ Cell Culture Inserts and measure immune function, then the answer is most likely.  Although it does not appear much published work has been done in this area, FluoroBlok inserts are a great choice when one is looking to exclude […]» Read More