SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company’s global leadership and world-class service and support in the capillary electrophoresis and liquid chromatography-mass spectrometry industry have made it a trusted partner to thousands of the scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research.
With over 40 years of proven innovation, SCIEX excels by listening to and understanding the ever-evolving needs of its customers to develop reliable, sensitive and intuitive solutions that continue to redefine what is achievable in routine and complex analysis. For more information, please visit www.sciex.com.
Achieving Detailed Characterization of mRNA-LNP Therapeutics and Vaccines with Cutting-Edge Technology
Activity in RNA-based drug research reached an all-time high thanks to the success of messenger RNA (mRNA) COVID-19 vaccines, which provided the pathway for clinical validation for this new modality. The great versatility of mRNA, ... Continued
More Fragments, Less Headaches: How Electron Activated Dissociation Can Improve Lipid Nanoparticle Analytics in Gene-Based Drug Development
In contrast to traditional biologics, drugs based on the delivery with lipid nanoparticles (LNPs) can be even more complex and pose new challenges from an analytical perspective. The genetic cargo and several different lipid classes ... Continued
The use of lipid nanoparticles (LNPs) as non-viral delivery tools for nucleic acid payloads, such as messenger RNA (mRNA), has become more widely adopted in the industry not only due to its use in COVID-19 ... Continued
A Multi-capillary Electrophoresis System Speeding Development Timelines for Biotherapeutics — Run Multiple Samples in Parallel with the BioPhase 8800 system
Today, we are analyzing more drug candidates with a wider range of modalities, all with the understanding that speed to market is more critical than ever before. As a result, scientists working on these candidates ... Continued
Liquid chromatography with tandem mass spectrometry (LC-MS/MS) is one of the most versatile and high-performance analytical tools for the detection, characterization and quantification of biotherapeutic molecules and vaccines. However, emerging modalities require new analytical methodologies ... Continued
Rapid Spent Media Analysis of Metabolites During Cell Line Development for Better Product Quality Outcomes
Spent media analysis is an important tool used to provide crucial information about the amino acids and nutrients that cells use during growth phase. Spent media analysis also provides details about the metabolites that are ... Continued
Oligonucleotides (OGN) are a class of therapeutics comprised of short strings of synthetic nucleotides. OGNs have the ability to to alter, suppress or restore expression of target genes associated with disease or health. This makes ... Continued
SCIEX’s new cell culture media analysis method has been designed to meet industry demands by providing solutions to the technical challenges present in current assay development methods. Thereby enabling a successful QbD approach for cell culture media optimization with critical quality attributes in mind. At-line monitoring strengthens QbD with the ability to monitor the impact of these components and how they change in-process....Continued