Polyplus-transfection® SA is a biotechnology company that develops and sells innovative solutions for the delivery of nucleic acids in research, bioproduction and therapeutics. Located close to the University of Strasbourg in Eastern France, Polyplus-transfection® is ISO 9001-certified since 2002 and supplies its wide range of reagents for the transfection of genes, oligonucleotides and siRNA through a worldwide distributor network. Polyplus-transfection® reagents are involved in a growing number of clinical trials worldwide. In addition, Polyplus-transfection® holds a broad estate of patents and licenses including original methods for therapeutic siRNA delivery.
Transfection Reagent Portfolio Enables Seamless Scalability from R&D to Commercial Therapeutic Viral Vector Manufacturing
Cell and gene therapies are achieving greater success in the clinic and as a result there is an increasing need to transition manufacturing from research scale to clinical and ultimately to commercialization. Critical to the manufacture of many gene-based therapies ... Continued
Transient protein production enables quick and efficient production of milligram to gram quantities of recombinant protein, which saves time and cost compared to developing a genetically stable cell line for use in bioproduction. This is particularly important in drug development ... Continued
Cool Tool: PEIpro® enables seamless scale-up of transient transfection for therapeutic viral vector manufacturing
During process development (PD) for virus vector production, choosing raw materials from reliable suppliers that can provide the highest quality to meet Advanced Therapy Medicinal Products (ATMP) GMP guidelines is key and will facilitate transition to large-scale clinical-grade virus manufacturing. ... Continued