- The Dish’s Weekly Biotechnology News Wrap Up – April 21, 2017Posted 4 days ago
- Glycosylation Overview and How to Control Glycosylation using In Vitro GlycoengineeringPosted 5 days ago
- A Novel Approach for Expansion of High Quality Mesenchymal Stem CellsPosted 6 days ago
- Cell Therapy Clinical Trials: Navigating the operational shift from Phase 1 to Phase 2Posted 1 week ago
- The Dish’s Weekly Biotechnology News Wrap Up – April 14, 2017Posted 2 weeks ago
- GMP Proteins for Cell Therapy Manufacturing: Top 6 Things to KnowPosted 2 weeks ago
- Smart Cell Culture Monitoring – Transforming the way we look at cells in culturePosted 2 weeks ago
- A Primer on Primary Cells and CulturePosted 2 weeks ago
- The Importance of Resin Selection in Development of a Platform Bioprocess FilmPosted 2 weeks ago
- The Dish’s Weekly Biotechnology News Wrap Up – April 7, 2017Posted 3 weeks ago
Sponsors & Partners
The Cell Culture Dish would like to thank our sponsor and partner companies for their support.
For over 30 years, the Cell Culture Company has been delivering biologics production solutions for preclinical to commercial stages, in mg to kg quantities. The organization serves the diagnostic, therapeutic and animal health industries. It is also home to the National Cell Culture Center, an NIH-founded initiative that provides subsidized services to academic research institutions.
Cell Culture Company is headquartered in Minneapolis, Minnesota. Its 33,000 square foot facility hosts corporate offices, hollow fiber bioreactor manufacturing and distribution operations, and GMP mammalian whole cell and protein production labs. Learn more at cellculturecompany.comm.
GE Healthcare Life Sciences provides tools and technologies, solutions and expertise which enable the biopharmaceutical industry to develop and manufacture biotherapeutic medicines and vaccines cost-effectively. Our products and platform solutions are designed to meet the key challenges posed at every stage in the biomanufacturing process, delivering the desired product at the required purity and safety: all with fast development and integrated solutions in mind. Across the bioprocessing spectrum, our focus is on supporting you from idea to result.
InVitria products allow users to eliminate animal components from their cell-based processes. Removing these components helps improve consistency, safety and efficiency. InVitria’s products are recombinant proteins that are manufactured using cGMP standards in our manufacturing facility in Junction City, Kansas. These products have many uses across the life science industry including in regenerative medicine, cellular therapy, biomanufacturing, vaccines, diagnostics and medical devices.
MaxCyte’s flow electroporation is driving the next generation of cell-based medicines. Used in the discovery, development, and manufacture of cell-based therapeutics, the MaxCyte GT® Flow Transfection System, MaxCyte STX® Scalable Transfection System, and MaxCyte VLX® Large Scale Transfection System enable the development of transfected cells for a range of applications.
STEMCELL Technologies Inc. is committed to providing specialized cell culture media, cell isolation products and accessory tools for life science research. Driven by science and a passion for quality, STEMCELL delivers more than 2000 products to over 80 countries worldwide. Researchers interested in human pluripotent stem cells and their downstream differentiation, hematopoietic stem and progenitor cells, mesenchymal stem cells and epithelial cells rely on our products and services for experimental efficiency, accuracy and reproducibility. We also offer normal and diseased primary cells, cultureware for bioengineering, instruments for high throughput analyses, and accessory tools such as antibodies, small molecules and cytokines to complete your cell biology workflow. STEMCELL Technologies provides consistent, unfailing quality and one-on-one assistance to help you succeed. We do this because we love science as much as you do.
Thermo Fisher Scientific, Inc. is a global biotechnology company dedicated to improving the human condition. Our systems, consumables and services enable researchers to accelerate scientific and medical advancements that make life even better. Thermo Fisher Scientific customers do their work across the biological spectrum, working to advance the fields of discovery and translational research, molecular medicine, stem cell-based therapies, food safety and animal health, and 21st century forensics. The company manufactures both molecular diagnostic and research use only products.
Beckman Coulter Life Sciences is dedicated to improving the health of people around the world. The company’s global leadership and world-class service and support delivers sophisticated instrument systems, reagents and services to life science researchers in academic and commercial laboratories, enabling new discoveries in biology-based research and development. Beckman Coulter manufactures, sells, supports and services complete centrifugation and automated liquid handling solutions. For more information, please visit www.BeckmanCoulter.com.
For over 30 years, Biological Industries (BI) – a global leader in cell culture media development, molecular and diagnostic tools, and stem cell research products – has been serving the life sciences industry in more than 50 countries worldwide. Today we are excited to announce Biological Industries USA (BI-USA), a new division headquartered in the United States. Researchers around the country will now have easy, direct access to BI’s entire portfolio of optimized, innovative solutions for general cell culture and stem cell research, as well as access to our dedicated technical experts and collaborations with our R&D scientists. BI offers the leading stem cell culture media NutriStem® – a serum-free; xeno-free stem cell media for the growth and expansion of pluripotent stem cells and mesenchymal stem cells. Bi also offers custom media formulations, products for mycoplasma detection and elimination, cell culture contamination prevention, and human cytogenetics products.
Our state-of-the-art research and manufacturing facilities are cGMP compliant and ISO-certified, with the highest levels of quality management systems in place. It is this level of unmatched commitment to quality along with our strong history of innovation and scientific expertise that defines BI’s culture of excellence. For more information please visit, www.bioind.com.
Bioproduction Group provides software toolsets and consultative engineering expertise to leading companies in the biomanufacturing industry. Bio-G has modeled over 25% of global biomanufacturing capacity and our software is used to optimize manufacturing capacity, scheduling, and long and short-term planning.
The Bio-G software suite consists of three applications, the first being our Real Time Modeling System (RTMS), which is the world’s fastest discrete event simulation toolset. Crosswalk is data acquisition software that seamlessly communicates with your corporate data sources such as SAP, DeltaV, Maximo, OSIsoft PI and other SQL based systems without the need of a database administrator or programmer. BioFit is a powerful Excel based, open source, facility fit software application that easily determines system and process constrains during process development or tech transfer. Bio-G software allows biomanufacturer’s to proactively identify and mitigate the risks and variability in their production processes, yielding significant improvements in run rates, capacity, schedule adherence, and solutions to a host of other critical problems. Visit us at www.bio-g.com for more information or to setup a live demonstration.
Charter Medical, Ltd. is a subsidiary of Fenner PLC (LSE: FENR). Charter Medical, based in Winston-Salem, NC, USA has 15,000 square feet of clean room space and is an ISO 13485 certified and FDA registered manufacturing facility. Charter Medical has a 25 year history of creating high-quality, single-use products and serves the bioprocessing, cell therapy and medical device industries. Focus is on designing and supplying single-use solutions for cell growth, frozen storage and biological fluid handling. Charter Medical is committed to providing quality products and services with an experienced staff dedicated to exceeding customer expectations from product development, delivery and implementation. www.chartermedical.com.
When it comes to scaling-up your big idea, you need a supplier who is as comfortable in the production suite as in the lab. Corning brings together the broadest selection of vessels, surfaces, and media to create an end-to-end solution for scale-up of anchorage-dependent and suspension cells. Find out how we can help you increase productivity, lower risk, and get your scale-up right from the start. Learn more at www.corning.com/lifesciences.
Irvine Scientific, a member of JX Group, is a worldwide leader in the innovation and manufacture of cell culture media, reagents, and medical devices for researchers and clinicians. The company provides unrivalled service and quality to scientists working in cell therapy and regenerative medicine, assisted reproductive technology and cytogenetics, and industrial cell culture for the large-scale production of biotherapeutics and vaccines. Irvine Scientific adheres to both ISO and FDA regulations and operates dual cGMP manufacturing facilities in California, USA and Tokyo, Japan. The company’s consultative philosophy combined with expertise in cell culture and compliance provides customers with unique capabilities and support. For over 40 years, Irvine Scientific has remained uniquely flexible and focused on media while becoming a strategic global leader in media products and services. Learn more at www.irvinesci.com
JSR Life Sciences Division is the biotechnology-focused business unit of JSR Corporation. JLS provides specialized materials and products to the biotech industry. JLS operates a network of manufacturing facilities, sales offices and R&D labs in key markets throughout North America, Europe and Asia-Pacific. JLS is focused on downstream bioprocessing materials for pharmaceutical manufacturing and diagnostics and research products.
In downstream processing, JLS manufacturers Amsphere™ A3, a next generation Protein A chromatography resin for advanced protein separation in downstream processing of therapeutic antibodies manufacturing.
Finesse Solutions, Inc. based in Silicon Valley California provides intelligent bioprocess management solutions. Our mission is to empower our clients with innovative single-use sensors, bioreactors, controllers and software for both upstream and downstream. In addition to our own products, we are the only supplier with integration expertise offering clients the independence to select any preferred supplier of key unit operations. Whether it’s a single-use bioreactor for research and development or a fully integrated Smartfactory, we have a bioprocess solution for our customers.
Our SmartParts, Smart Systems and SmartMES platforms enable better performance, intelligence and flexibility.
For more information, please visit us at www.finesse.com.
Drawing on nearly 70 years of experience supporting cGMP manufacturing of vaccines and protein-based therapeutics, Pall Life Science’s innovative cell therapy platform is designed to help our customers overcome the challenges associated with the production of live cells for therapies. Pall is dedicated to helping our customers achieve their cell therapy commercialization goals. Learn More at www.pall.com/celltherapy.
Bio-Techne brings together the prestigious life science research brands of R&D Systems, Novus Biologicals, Tocris Bioscience, and Protein Simple to provide stem cell researchers with high-quality reagents to optimize and standardize their workflow. In addition to producing consistent and robustly-active growth factors and small molecules for stem cell expansion and differentiation, our in-house developed specialized media, differentiation kits, and verification kits are being used globally to make advancements in stem cell research.
Essential Pharmaceuticals, LLC, is based in Ewing, NJ, and provides medical researchers and manufacturers new tools to bring performance, convenience, and control to enhance the advancement of basic research and drug discovery. Essential Pharmaceuticals offers products that support the preservation and growth of human systems. From the cell to the entire organ, we look to advance medical treatments and the research that creates new medical treatments.
Established in 2006 Essential Pharmaceuticals launched Custodiol® HTK organ preservation solution. Essential continues to invest and develop the Custodiol business in the medical device marketplace. Essential’s search to preserve organs led it to start looking at how to preserve the cells of the organs themselves. With the leadership of Essential’s new Chief Science Officer, this led to developing the “Ess” line of research products.
After three years of development, Essential Pharmaceuticals has three new products ready for the market:
- Cell-Ess®: A serum free, totally synthetic serum replacement used to culture cells
- Clin-Ess®: An animal component free medium that can preserve tissue samples for study and diagnostic testing at refrigerated temperatures.
FUJIFILM Diosynth Biotechnologies is a world leading cGMP Contract Development and Manufacturing Organization supporting our partners in the biopharmaceutical industry in the development and production of their therapeutic candidates. As a global organization we operate as a network with locations in Research Triangle Park, North Carolina, USA; College Station, Texas, USA and Billingham, United Kingdom. As a partner to our customers, we bring extensive process and analytical development and cGMP manufacturing experience to meet your needs at every stage of the product lifecycle, from efficient protein expression, process design and cGMP manufacture, through to process validation, commercial production, and post approval product lifecycle management.
For more than 75 years, Kerry has earned its reputation for reliability and excellence in serving the biotech, pharmaceutical, and nutrition markets. We deliver innovative solutions to assist customers increase cell proliferation, extend cell viability, and increase target protein production in biotechnological production systems.
Every day we expand our capabilities to meet the changing needs of the biotech market. Kerry’s products have evolved with market trends in cell culture over the last fifty years to fulfil our customers’ requirement and has grown to encompass modern plant based hydrolysates, yeast extracts, recombinant proteins, cell line tailored supplement systems, and chemically defined medium. We have the vast global resources and technical platform to deliver consistent, high-quality products backed by unparalleled service, technical support, and formulation customization capabilities.
MilliporeSigma, a life science leader, is a business of Merck KGaA, Darmstadt, Germany. We offer products to safely and efficiently develop and manufacture therapeutics. Our products and services include single-use manufacturing, filtration, chromatography and purification, virus reduction, pharma and bio-pharma raw materials, drug delivery compounds, validation services and biopharmaceutical training. With the acquisition of Sigma-Aldrich, we now have the largest offering of products and services for formulations, actives and biotechnology processes.
Ovizio is an innovative Belgian company developing smart quantitative microscopy solutions for life science applications.
Ovizio technology offers machine learning, label-free and non-invasive tools for real-time 3D imaging of living cells. Validated with almost every type of transparent cell culture vessel, Ovizio’s devices can track cell density, cell morphology and cell viability with the highest reproducibility at a single cell level. Applicable from R&D to manufacturing processes and enabling significant cost reductions as well as Quality improvement, Ovizio’s microscopes are robust and perfectly suited for automated cell culture monitoring, analysis, PAT and Quality control. Learn more at www.Ovizio.com
The Custom Biotech division of Roche Diagnostics offers a range of innovative products and services for the biopharmaceutical and cell therapy markets, customizable to meet your unique quality and regulatory needs. Some specific product categories include research and GMP enzymes for cell isolation and passaging, high resolution automated cell culture analysis system, photometric-based instrumentation for monitoring nutrients and metabolites relevant to cell culture processing and cell health, and mycoplasma test methods for in-process and product release quality assurance. With our extensive industry experience and strong customer orientation, Custom Biotech is committed to helping you achieve success across all stages of the development process.
Solentim is dedicated to the development of innovative tools to shorten steps in the upstream cell line development workflow. Commercial cell line development for biopharmaceutical production is an intrinsically high value process which takes a significant amount of time and skilled resource.
Our Cell Metric™ product range consists of simple bench-top imaging stations for specifically providing indisputable documentary evidence of clonal origin for a commercial cell line as part of a regulatory submission package.
Cell Metric™ now enables companies to do only a single round of cloning and hence eliminate several weeks from their cell line development process.
… Imaging tools to accelerate upstream cell line development
StemBioSys, Inc. is a privately-held biomedical company focused on enabling optimized isolation, growth and delivery of adult stem cells for research, therapeutic or drug discovery applications. Its patented technology platforms – licensed from the University of Texas Board of Regents – overcome key obstacles to creating clinically useful stem cell therapies. The centerpiece of these enabling technologies is the HPMEâ (High Performance Micro Environment) platform. This cell derived 3-dimensional microenvironment allows a variety of stem cells to replicate more rapidly, maintain a small cell size and express markers indicative of retained stem cell potency beyond that seen with more traditional tissue culture substrates. StemBioSys’ first commercial product BM-HPME®, is currently available to stem cell research market. With directed collaborations and further research we hope to extend the disruptive technology presented by our HPME® platform to drug discovery and therapeutic applications.
If you would like information on becoming a sponsor please email the dish